Our current understanding of adrenal function is still at its infancy at best. It is therefore very difficult for any health professional to have a good grasp of the Adrenal Fatigue condition from a purely pathological and physiological perspective. The number of physicians with true expertise in advanced Adrenal Fatigue is very small. Those who are good in this gain their expertise not from textbooks, but from years of clinical experience. There is no short cut, because text-book cases are few and far between. Because the full recovery cycle can take years to complete in severe cases, practitioners with little experience will find it hard to handle cases other than the most mild and straight forward ones.
Combined pituitary hormone deficiency (including ACTH deficiency) due to genetic pituitary abnormalities is rare. ACTH and cortisol deficiency have been described in patients with multiple pituitary hormone deficiencies due to mutations in the PROP-1 (Prophet of Pit-1) gene, even though PROP-1 is not expressed in corticotropes. The onset of cortisol deficiency, which may be severe, ranges from childhood to late adulthood [ 2-5 ]. Mutations in other transcription factors involved in early pituitary development (HESX1, LHX4) also can result in variable degrees of hypopituitarism that include ACTH deficiency [ 6,7 ]. (See "Causes of hypopituitarism", section on 'Genetic diseases' .)
this information is just plain wrong. this is a perfect example of blog-doctor gone wrong. it would take me all day to correct this misleading garbage. people if you suspect you have a hormonal disorder see an endocrinologist….end of story. the entire premise that adrenal fatigue would cause weight gain is false. its quite to the contrary. adrenal fatigue causes weight loss. lack of cortisol=hypoglycemia=weight loss…period. adrenal fatigue is at a rate of approx. 1:100,000 so doubt that is your problem ladies…your problem is actually extremely simple…you are eating more calories than your burning. throw out the potato chips. cancel your netflix subscription. stop watching game of thrones…and maybe go out for a run.