My 6 year old cat has been on a long term prednisone direct injection treatment for the past 5 years due to her oral autoimmune disease. My veterinarian and I decided this was a better option, due to her young age at diagnosis, than the typical solution of removing all of her teeth. Her shots are infrequent (~every 8-12 weeks) to reduce the occurrence of side effects or long term damage from the steroids. The effect has been amazing! She went from constantly lethargic to playful in a matter of days and has remained that way. To date she has only lost 3 teeth which is impressive considering the other option of having them removed. It means frequent visits to the vet’s office and monitoring but it is well worth it for her improved quality of life.
Do not stop giving your pet these drugs abruptly, as this can have life-threatening consequences. Ask your vet about weaning your dog off of them slowly. You should let your veterinarian know if your dog is on any other medications, as these can react badly with prednisone or prednisolone. A vet should be consulted for dogs that are pregnant, and puppies that are too young should not get these drugs as they can inhibit growth and cause other problems. Diabetic dogs should also not take them. Overdose can lead to itching, seizures, loss of hearing, weakness, anxiety, depression, high blood pressure, or heart problems. Follow your veterinarian’s dosage guidelines and contact your vet if you see signs of any serious symptoms.